Being a man, not being married, and having a low income are some of the factors which new research has shown can increase your risk of dying from COVID-19. This research was conducted by a team at Stockholm University in Sweden and the findings were published in the journal Nature Communications.

The research team combed through the data available at the Swedish National Board for Health and Welfare on the known COVID-19 fatalities in the country. The researchers were specifically interested in the deaths of people aged 20 or older. The statistics studied were from the onset of the pandemic until May 7, 2020.

Information obtained from Statistics Sweden yielded data on the victims’ city of residence, level of education, country of birth, marital status, and age.

The data showed that single people were more likely to die from the novel coronavirus when compared to those who are married. Two possible reasons explain this, according to the researchers.

First, people who are in poor health may be less likely to attract marriage partners, and when the pandemic struck, these people were more likely to succumb to the disease due to their already weakened health status.

Secondly, single people don’t have a protective social system around them, and this makes these individuals more vulnerable in the face of the pandemic. For example, individuals who are surrounded by family are likely to receive better support and care when they are infected by the virus, and this will increase the likelihood of full recovery.

Males were also found to be more susceptible to dying from the virus, and this was attributed to a number of factors, such as lifestyle and biology. For instance, men are more risk-taking when compared to women. This potential for risky behavior increases the chance that men will be exposed to, and eventually succumb to COVID-19. Men also generally take longer to admit that something is amiss, and this gives the infection an opportunity to progress before the person seeks medical help.

People with low education and low incomes also seem to have high COVID-19 mortality outcomes. When one’s income is low, the person is less likely to put their health at the top of their list of priorities (they must keep working to feed their families, for example). These lifestyle factors make low income and low education a strong factor in coronavirus mortality.

In many respects, this research doesn’t depart a great deal from other studies which have looked at the factors behind mortality due to different health conditions. For this reason, entities like DarioHealth Corp. (NASDAQ: DRIO) are unlikely to find any new information from the Swedish research with the exception of its focus on COVID-19.

About BioMedWire

BioMedWire (BMW) is a bio-med news and content distribution company that provides (1) access to a network of wire services via NetworkWire to reach all target markets, industries and demographics in the most effective manner possible, (2) article and editorial syndication to 5,000+ news outlets (3), enhanced press release services to ensure maximum impact, (4) social media distribution via the Investor Brand Network (IBN) to nearly 2 million followers, (5) a full array of corporate communications solutions, and (6) a total news coverage solution with BMW Prime. As a multifaceted organization with an extensive team of contributing journalists and writers, BMW is uniquely positioned to best serve private and public companies that desire to reach a wide audience of investors, consumers, journalists and the general public. By cutting through the overload of information in today’s market, BMW brings its clients unparalleled visibility, recognition and brand awareness. BMW is where news, content and information converge.

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• 180 Life Sciences is a clinical-stage biotechnology company developing anti-tumor necrosis factor (“TNF”) therapies to treat a variety of inflammatory conditions.
• Phase 2b/3 clinical trials on fibrosis and inflammation-causing TNF irregularity are currently underway with first results expected in 2021
• The company is to be acquired by a SPAC (NASDAQ: KBLM) and will be listed on the Nasdaq Capital Market under ticker symbol ATNF

Pioneering biotech company, 180 Life Sciences Corp. is bringing hope to sufferers of Dupuytren’s Disease and other inflammatory conditions caused by an impaired immune system. Currently, the company has three major programs underway focused on therapies for separate areas of inflammation. These programs are headed by a team of renowned scientists who have already developed blockbuster drugs, discovered an entire drug class and made ground-breaking discoveries in their fields. The programs are exploring therapies expected to bring relief to those afflicted by a variety of TNF conditions, including ‘frozen shoulder,’ Dupuytren disease, postoperative cognitive dysfunction (“POCD”), and non-alcoholic fatty liver disease (“NAFLD”).

TNF is one of those good things, a surfeit of which, can turn out bad. A protein released by white blood cells to mobilize the body’s defenses, i.e. the immune system, TNF plays an essential role in fighting off diseases of many kinds. TNF triggers inflammation to create an environment conducive to healing infected or damaged tissue. Typically, this state of affairs continues just long enough to repair damage to the cells. Regular or acute inflammation lasts for a short time, going away within hours or days. But sometimes, TNF sets the inflammatory process in motion when there’s no threat, a situation that can persist for a lengthy period, leading to what is known as chronic inflammation. Chronic inflammation opens a Pandora box of ailments. Conditions linked to chronic inflammation include Alzheimer’s disease, asthma, cancer, diabetes, heart disease, and a number of others that 180 Life Sciences Corp. is currently conducting research on.

The Company’s Three Research Programs Are: 

The fibrosis and anti-TNF program, based at the Kennedy Institute, University of Oxford, U.K.

The program is addressing four critical areas of inflammation:

• Dupuytren disease, a debilitating condition that causes the fingers to irreversibly curl toward the palm. Dupuytren disease affects some 15 million Americans over the age of 35, about 5 percent of the U.S. population, according to a 2014 CDC study (https://nnw.fm/EkAff). Top line data from Phase 2b/3 trials are expected by Q4 2021.
• Frozen shoulder is a musculoskeletal impairment that makes it difficult or impossible to move the shoulders (https://nnw.fm/z1sYI). Phase 2b trials are set to begin Q3 2021.
• POCD affects patients, particularly older ones, after surgical operations. In one study, roughly 12 percent of patients over age 60 had postoperative cognitive dysfunction, three months after surgery (https://nnw.fm/sd9OI). Phase 2 trials in POCD are anticipated to commence in Q4 2021.
• Nonalcoholic steatohepatitis (“NASH”) is a type of non-alcoholic fatty liver disease, aggravated by hepatitis (https://nnw.fm/9fn00). Preclinical studies in liver fibrosis and NASH are set to begin in late 2020.

 Synthetic CBD Analogs (“SCAs”) – Preclinical – based at the Hebrew University of Jerusalem

The SCA program is based at the Hebrew University of Jerusalem, in Israel, with additional research and trials at the Kennedy Institute, at the University of Oxford.

180 Life Sciences is aiming to develop SCAs that are safe and non-psychoactive and formulated to improve efficacy, as an alternative to naturally occurring cannabidiol (“CBD”). The program is led by a team that includes Professor Raphael Mechoulam, the first to ‘discover’ tetrahydrocannabinol (“THC”). 180 Life Sciences is aiming to create a compound that is 99.5% pure CBD, which will drastically improve medical prescriptive precision. The program is also exploring a drug delivery platform—ProNanoLipospheres (“PNL”)—to improve bioavailability.

The α7nAChR program, based at Stanford University in the US.

The α7nAChR program is searching for an effective therapy to treat ulcerative colitis in ex-smokers. α7nAChR is a nicotine receptor and is a central factor in the body’s method of controlling inflammation.

180 Life Sciences Corp. is to be acquired by KBL Merger Corp. IV (NASDAQ: KBLM), a special purpose acquisition corporation (“SPAC”), after which the combined entity will be listed on Nasdaq under the ticker symbol: ATNF.

For more information, visit the companies’ websites at www.180LifeSciences.com and www.KBLMerger.com.

NOTE TO INVESTORS: The latest news and updates relating to 180 Life Sciences are available in the company’s newsroom at http://nnw.fm/180

About NetworkNewsWire

NetworkNewsWire (NNW) is a financial news and content distribution company that provides (1) access to a network of wire services via NetworkWire to reach all target markets, industries and demographics in the most effective manner possible, (2) article and editorial syndication to 5,000+ news outlets (3), enhanced press release services to ensure maximum impact, (4) social media distribution via the Investor Brand Network (IBN) to nearly 2 million followers, (5) a full array of corporate communications solutions, and (6) a total news coverage solution with NNW Prime. As a multifaceted organization with an extensive team of contributing journalists and writers, NNW is uniquely positioned to best serve private and public companies that desire to reach a wide audience of investors, consumers, journalists and the general public. By cutting through the overload of information in today’s market, NNW brings its clients unparalleled visibility, recognition and brand awareness. NNW is where news, content and information converge.

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• SGTM awarded contract for tree services in Lake County, Florida through subsidiary Central Florida Arborcare
• SGTM subsidiary Mulch Manufacturing recently awarded two additional packaging contracts
• Subsidiary ArborPro of Mississippi Inc. awarded contract for Hurricane Laura recovery efforts
• Q2 results include $12.3 million revenue and $3.4 million gross profit

Sustainable Green Team (OTC: SGTM), a leading provider of environmentally-beneficial solutions for tree and storm waste disposal, recently announced that Central Florida Arborcare, its wholly-owned subsidiary, was awarded a one-year contract to supply tree trimming and related services to the county, renewable for an additional four times over a one-year period. Along with tree services, SGTM provides debris hauling and waste removal as part of its overall operations that transform organic waste into environmentally-friendly products such as mulch and playground surfacing material.

“Getting awarded this contract is allowing us to stay on point with our growth, building relationships with municipalities and governments,” said SGTM CEO and Director Tony Raynor (https://nnw.fm/IoXrd). “We are very fortunate to be an essential business that has proven to stand strong through these economically hard times.”

Despite the economic hardships currently being experienced by businesses across the country, SGTM has grown. The new contract comes shortly after subsidiary Mulch Manufacturing Inc. was awarded a 2021 mulch packaging contract renewal from Menards Inc., the third-largest home improvement chain in the U.S. with 350 stores in operation across 15 states. Also in the pipeline for Mulch Manufacturing is another contract with Old Castle Lawn & Garden to supply large home improvement chains in the Midwest. ‘

SGTM takes its role as a caretaker of the environment seriously by providing remediation efforts in the wake of hurricanes and other natural disasters such as Hurricane Laura. Through its strategic partner, ArborPro of Mississippi Inc., SGTM contributed to recovery efforts in Louisiana by providing services that diverted damaged trees and other vegetation from landfills. The busy hurricane season is expected to contribute significantly to the company’s bottom line this quarter, building upon already impressive Q2 results that included over $12.3 million in revenue and $3.4 million in gross profit (http://nnw.fm/iiGDM).

SGTM plans to expand operations through a combination of organic growth, national partnerships and strategic acquisitions. The company’s strong commitment to environmental sustainability was a primary factor behind the recent name and ticker change from National Storm Recovery Inc. (OTC: NSRI) to Sustainable Green Team, Ltd. (OTC: SGTM). Along with driving forward its mission, the company also aims to maximize value to shareholders seeking ethical investment opportunities in businesses with significant growth potential that can withstand increasingly challenging economic conditions.

To learn more about Sustainable Green Team Ltd., view the investor presentation at http://nnw.fm/UpXmd.

NOTE TO INVESTORS: The latest news and updates relating to SGTM are available in the company’s newsroom at http://nnw.fm/SGTM

About NetworkNewsWire

NetworkNewsWire (NNW) is a financial news and content distribution company that provides (1) access to a network of wire services via NetworkWire to reach all target markets, industries and demographics in the most effective manner possible, (2) article and editorial syndication to 5,000+ news outlets (3), enhanced press release services to ensure maximum impact, (4) social media distribution via the Investor Brand Network (IBN) to nearly 2 million followers, (5) a full array of corporate communications solutions, and (6) a total news coverage solution with NNW Prime. As a multifaceted organization with an extensive team of contributing journalists and writers, NNW is uniquely positioned to best serve private and public companies that desire to reach a wide audience of investors, consumers, journalists and the general public. By cutting through the overload of information in today’s market, NNW brings its clients unparalleled visibility, recognition and brand awareness. NNW is where news, content and information converge.

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Days characterized by extreme air pollution and extreme high heat are increasing in frequency in different parts of the world. For example, New Delhi in India experienced a week of the worst ever air pollution that had ever been recorded anywhere in human history in November last year. Shortly before that extreme event, Western Europe saw two heatwaves that left at least 1,500 people dead. These developments prompted a team at Texas A&M University to investigate what would happen if extreme heat coincided with extreme air pollution.

The researchers used a computer model to analyze the likelihood of extreme heat and extreme air pollution coinciding in South Asia. This particular computer model used data on the trends of greenhouse gas emissions, population growth, effects of terrain, weather and oceans on air pollution.

Based on their findings, the researchers predict that there is going to be a massive increase in the number of days that feature both extreme heat and extreme air pollution by 2050. In fact, a 175% increase, amounting to 78 days of extreme air pollution and extreme heat, is predicted.

The researchers selected South Asia because this part of the world is a red zone on matters of climate change, and its population is expected to reach 2 billion in 2050 from the current 1.5 billion.

Furthermore, the computer model revealed to the research team that the land area affected by the double whammy of extreme air pollution coinciding with extreme high heat would balloon tenfold from the year 2000 to 2050. This land area is expected to host 25% of all the people in South Asia, up from the current 2%. Why should these extreme weather events concern us?

It is a known fact that extreme air pollution and extreme high heat have adverse effects on human health. Experts say biomed companies like Processa Pharmaceuticals Inc. (NASDAQ: PCSA) are likely to agree that cases of heat stroke and heat exhaustion increase each time ambient temperature rises to heat wave levels. Additionally, chronic health conditions, such as heart disease, worsen under such conditions.

In the same vein, extreme air pollution plays a significant role in the onset or exacerbation of asthma, pregnancy complications, heart disease as well as other serious health conditions.

The researchers therefore fear that people with these health conditions could be severely affected when a combination of extreme heat and extreme air pollution coincide as it has been known for long that exposure to additional environmental stressors worsens an individual’s susceptibility to the adverse effects of each of the existing stressors.

The team suggests that additional studies need to be done to establish who exactly is at risk from extreme weather events. And collective action needs to be taken to avert the worse-case scenario predicted by the computer model. Ramping up green energy solutions is one way to reduce CO2 emissions, for example.

About BioMedWire

BioMedWire (BMW) is a bio-med news and content distribution company that provides (1) access to a network of wire services via NetworkWire to reach all target markets, industries and demographics in the most effective manner possible, (2) article and editorial syndication to 5,000+ news outlets (3), enhanced press release services to ensure maximum impact, (4) social media distribution via the Investor Brand Network (IBN) to nearly 2 million followers, (5) a full array of corporate communications solutions, and (6) a total news coverage solution with BMW Prime. As a multifaceted organization with an extensive team of contributing journalists and writers, BMW is uniquely positioned to best serve private and public companies that desire to reach a wide audience of investors, consumers, journalists and the general public. By cutting through the overload of information in today’s market, BMW brings its clients unparalleled visibility, recognition and brand awareness. BMW is where news, content and information converge.

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• Predictive Oncology’s CEO Carl Schwartz published open letter to company’s shareholders
• Schwartz elaborated on various developments within each of POAI’s divisions, has reiterated his optimism on company’s operations going forward
• CEO also revealed that company’s revenue trends have stabilized and are now on upward trend with cash burn beginning to decline
• Company also revealed its ability to access over $10 million in undrawn equity lines of credit

Carl Schwartz, the CEO of Predictive Oncology (NASDAQ: POAI), a knowledge-driven medicine company that focuses on applying data and artificial intelligence (“AI”) to cancer personalized medicine and drug discovery, has recently published a letter to the company’s shareholders elaborating on the company’s latest achievements as well as their prospects going forward (https://ibn.fm/L1mA8).

Within his letter, Schwartz addressed the latest developments within each of the company’s business verticals and stressed that in spite of the tumultuous global economy, Predictive Oncology was witnessing both stable and rising revenues along with declining levels of cash burns. Schwartz also detailed that the company’s balance sheet was still quite resilient with access to over $10 million in equity capital able to be drawn down from their existing lines of credit.

The letter also elaborated on the company’s various operational divisions, commencing with its Skyline Medical division. Skyline Medical is charged with the manufacture and sale of POAI’s groundbreaking, FDA-cleared STREAMWAY System – providing medical facilities with a direct-to-drain fluid disposal system intended to automate the collection, measurement and disposal of waste fluids during medical procedures. POAI revealed that the division was now self-supporting from a cash standpoint, with sales of disposables used on Streamway machines more than covering the business’ operating expenses. Separately, the company explained that the continued sale of new Streamway devices would also add to the future potential revenues which the company could derive from the sale of disposables.

Schwartz also touched upon the company’s Helomics division, which seeks to assist pharmaceutical, diagnostic and biotech industries develop predictive models of how tumors could respond to drugs. Helomics recently launched a restructured clinical test offering to clinicians for ovarian cancer, which has been very well received by oncologists. The company expects that this new test, coupled with Helomic’s existing product range, will be revenue generating by year end and should be able to cover the bulk of the division’s operating expenses going forward.

Elsewhere, Predictive Oncology also provided an update on subsidiary TumorGenesis, which specializes in the field of ovarian cancer, creating laboratory-grown cancer cells which can then be used to assist researchers and clinicians identify which cancer cells bind to specific biomarkers. TumorGenesis will be introducing its Ovarian Cell Line Media at the upcoming BIO-Europe Conference, which will allow researchers to isolate and successfully culture ovarian cancer cells that have not previously been cultured. Separately, the division is also in the process of registering with the US government as a contractor for developmental work in cancer cell capture and screening of compounds for the prevention and treatment of cancer.

Finally, Schwartz discussed the ongoing progress at Soluble Biotech, a subsidiary which seeks to provide optimized FDA-approved formulations for vaccines, antibodies and other protein therapeutics in a faster and lower cost basis to its customers. Having already secured a sizable contract, POAI’s management have expressed their confidence in the business generating revenues by the end of 2020.

With a number of ongoing positive developments taking place across Predictive Oncology’s various businesses, the company’s CEO has reaffirmed his positive stance on POAI’s corporate prospects, expressing his firm belief in the fourth quarter’s being “eventful”.

For more information about the company, visit www.Predictive-Oncology.com.

NOTE TO INVESTORS: The latest news and updates relating to POAI are available in the company’s newsroom at http://ibn.fm/POAI

About BioMedWire

BioMedWire (BMW) is a bio-med news and content distribution company that provides (1) access to a network of wire services via NetworkWire to reach all target markets, industries and demographics in the most effective manner possible, (2) article and editorial syndication to 5,000+ news outlets (3), enhanced press release services to ensure maximum impact, (4) social media distribution via the Investor Brand Network (IBN) to nearly 2 million followers, (5) a full array of corporate communications solutions, and (6) a total news coverage solution with BMW Prime. As a multifaceted organization with an extensive team of contributing journalists and writers, BMW is uniquely positioned to best serve private and public companies that desire to reach a wide audience of investors, consumers, journalists and the general public. By cutting through the overload of information in today’s market, BMW brings its clients unparalleled visibility, recognition and brand awareness. BMW is where news, content and information converge.

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The World Economic Forum estimates that robotics and automation can avert about 10,000 injuries within the metals and mining industries in just a decade, and that autonomous hauling could improve productivity by at least 15-30%. These figures are realistic and they highlight why autonomous mining should be pursued with urgency. Here are some of the things that need to happen for autonomous mining to become a widespread reality.

Establish the Foundation

For fully autonomous mining to exist, a core IT architecture needs to be set up so that every piece of mining equipment can communicate seamlessly with the different systems at the site. For example, it would be disastrous if a Hitachi excavator on site cannot communicate with a Caterpillar truck hauling materials off the site.

Cyber-security also needs to be carefully thought about and enhanced to avert the catastrophes which can result if hackers ever get control of the autonomous mining operations.

Data Readiness is a Must

Lots of data from numerous sources is needed to avail the raw material which analytics tools and artificial intelligence systems need to support all the decision-making processes during mining. Mining companies therefore have to prepare to capture as well as manage constantly growing volumes of data while at the same time making sure that all that data can be trusted and relied upon as the autonomous systems are making decisions.

If data readiness isn’t achieved, automation would be hard to implement, or it would be severely limited in scope.

Manage the Change

If a mining enterprise is to succeed at fully automating its mining operations, companies like Energy Fuels Inc. (NYSE American: UUUU) (TSX: EFR) would need to invest heavily in reskilling and retraining their employees so that they can be ready to work in the new autonomous setting. While some people may think that automation leads to job cuts, the truth is that many more jobs are created than those which are lost. The only difference is that the new jobs available aren’t along the same lines as those which previously existed.

For example, undergoing training as a mining truck driver isn’t wise when automation is looming. Rather, getting skilled as a data analytics specialist or data scientist, or even as an autonomous truck maintenance technician is a lot more forward-looking.

As the years roll by, there is likely to be a shift towards even greater environmental and human safety. This focus will compel mining entities to make gradual shifts to full automation, and as that momentum builds, autonomous mining will become the norm.

About MiningNewsWire

MiningNewsWire (MNW) is a specialized communications platform focused on developments and opportunities in the global resources sector. The company provides (1) access to a network of wire services via NetworkWire to reach all target markets, industries and demographics in the most effective manner possible, (2) article and editorial syndication to 5,000+ news outlets (3), enhanced press release services to ensure maximum impact, (4) social media distribution via the Investor Brand Network (IBN) to nearly 2 million followers, and (5) a full array of corporate communications solutions. As a multifaceted organization with an extensive team of contributing journalists and writers, MNW is uniquely positioned to best serve private and public companies that desire to reach a wide audience of investors, consumers, journalists and the general public. By cutting through the overload of information in today’s market, MNW brings its clients unparalleled visibility, recognition and brand awareness. MNW is where news, content and information converge.

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According to the work of Rutgers researchers published in the journal Epigenetics, kids who are born to diabetic mothers are prone to aging faster biologically and they may also be more susceptible to high blood pressure and obesity later in life.

The study analyzed more than 1,000 Chinese children born by mothers who had diabetes during pregnancy in order to understand their biological aging process. Of interest to the research team was the in utero exposure of the kids to diabetes and how that affected DNA methylation. Epigenetic methylation looks at how exposure to different conditions and environments accelerates or slows down the aging process at a cellular level.

Scientists can determine whether your DNA methylation matches with your chronological age or makes you biologically older than you actually are in terms of the years one has spent on earth. Individuals with a higher DNA methylation have been linked to a higher propensity to develop high blood pressure as well as other poor health outcomes later in life.

For this particular study, the team of researchers focused on 1,156 kids in Tianjin, China. The kids were aged between three and ten years old. When the epigenetic age of these kids was measured, it was found that all the children who were born to mothers that had diabetes while pregnant were biologically older than their chronological age.

This higher epigenetic age relative to the chronological age of the kids puts those children at a higher risk of having a higher BMI (body-mass index, a measure of whether someone is overweight, obese or of normal weight for their height). The kids were also found to be prone to having a higher percentage of body fat and a larger upper arm circumference.

Stephanie Shiau, the lead author of the study who also works as an instructor at the Rutgers School of Public Health, says that the findings show that gestational diabetes could have long-term adverse effects on the cardiometabolic health markers of the individuals.

This research makes a strong case for additional longitudinal studies (research which follows up the study subjects several years after the initial study) to get additional data about the link between one’s epigenetic age and the future onset of metabolic diseases in adulthood.

According to the National Institutes of Health (“NIH”), about 2-10% of all pregnancies in the U.S. are affected by gestational diabetes. This means that millions of kids are at high risk of developing the health problems linked to their higher epigenetic age.

DarioHealth (NASDAQ: DRIO), a global digital therapeutics company serving its users with dynamic mobile health solutions, is a company operating within the diabetes management market to keep an eye on.

About BioMedWire

BioMedWire (BMW) is a bio-med news and content distribution company that provides (1) access to a network of wire services via NetworkWire to reach all target markets, industries and demographics in the most effective manner possible, (2) article and editorial syndication to 5,000+ news outlets (3), enhanced press release services to ensure maximum impact, (4) social media distribution via the Investor Brand Network (IBN) to nearly 2 million followers, (5) a full array of corporate communications solutions, and (6) a total news coverage solution with BMW Prime. As a multifaceted organization with an extensive team of contributing journalists and writers, BMW is uniquely positioned to best serve private and public companies that desire to reach a wide audience of investors, consumers, journalists and the general public. By cutting through the overload of information in today’s market, BMW brings its clients unparalleled visibility, recognition and brand awareness. BMW is where news, content and information converge.

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• CNS Pharmaceuticals is a pre-clinical-stage developer of novel brain cancer-fighting drugs, including its lead candidate Berubicin
• The company is working to build on promising results from a 2006 Phase I trial, which provided 44 percent of its limited patient pool with clinically significant improvement in disease stability and one patient with a durable complete response (no evidence of any tumor remaining) for over 14 years
• CNS Pharmaceuticals expects to launch a pivotal Phase II trial of Berubicin at the beginning of next year and has been assembling a team of partner companies help with the trial
• CNS recently announced that the partner contracted to manufacture the Active Pharmaceutical Ingredient (API) for Berubicin has received a Certificate of Analysis necessary for the drug substance to be used in the clinical trial
• The company is also preparing in collaboration with its sub licensed partner, WPD Pharmaceuticals, for the first Phase I pediatric trial of Berubicin
• CNS is continuing the pre-clinical development of the company’s second promising cancer-fighting drug candidate, WP1244

Houston, Texas-based biopharmaceutical company CNS Pharmaceuticals (NASDAQ: CNSP) continues to achieve milestones in its drive to defeat glioblastoma multiforme (“GBM”), a relentless type of brain tumor known for very rapid progression and very short survival periods in nearly all patients once they’ve been diagnosed.

“If you get glioblastoma, the sad fact is you’re going to die from that disease,” CNS Pharmaceuticals CEO John Climaco told attendees at the Oppenheimer Fall Healthcare Life Sciences & MedTech Summit in September during a discussion about the aggressive brain tumors and the company’s investment potential as it advances tumor-fighting drug candidates (https://ibn.fm/t13u4). “We believe that [our drug candidate] Berubicin could potentially be a game-changer,” Climaco continued.

CNS Pharmaceuticals is in the process of developing the testing infrastructure for its its lead novel drug candidate, an anthracycline called Berubicin. The company announced at the beginning of this month that a partner company contracted to manufacture Berubicin active pharma ingredient (API) received a Certificate of Analysis, clearing it for use in the production of the Berubicin drug product in preparation for use in the clinical trial (https://ibn.fm/N2AMO).

Berubicin has shown the potential to stand out from other tumor-killing anthracyclines because it has the ability to cross the human body’s Blood-Brain Barrier (“BBB”) and sequester itself preferentially in tumor tissue, the company’s website states (https://ibn.fm/F8SNr).

The blood-brain barrier is a wall of specialized endothelial cells that separate the blood circulatory system from the brain and kick out recognized toxins such as anthracyclines before they can affect the body’s central nervous system. “That’s why anthracyclines kill glioblastoma cells in test tubes but don’t affect glioblastoma tumors when given to people,” the website states.

In a limited Phase I trial conducted in 2006, Berubicin showed evidence of prompting improved survival in a patient population that has a median survival rate of only 14.6 months from the date of the disease’s diagnosis, and one of the trial’s patients remains cancer-free as of the last assessment on Feb. 20 of this year, approximately 14 years later, Climaco said.

Tumors are generally first removed surgically to the extent possible, but then tend to recur.

The pharmaceutical temozolomide has been shown useful as a first-line response in temporarily extending the lifespan of fewer than 40 percent of GBM patients with a specific genetic variation, but even nearly all of those patients develop resistance to temozolomide within about a year’s time and CNS hopes to present Berubicin as a second-line therapy.

The contracts with drug manufacturers Pii and BSP will provide drug product for CNS’s Phase II clinical trial as well as two trials in Poland to be conducted by sub licensee partner, WPD Pharmaceuticals, including a Phase 2 adult trial and a first-ever Phase 1 pediatric trial, both of which are expected to launch during Q1 of 2021. The company recently announced an agreement with medical imaging company Image Analysis Group (“IAG”) to evaluate the upcoming clinical trial imaging results in real time using AI-driven technology (https://ibn.fm/TlKhu).

CNS Pharmaceuticals is also conducting pre-clinical development on a drug candidate known as WP1244 that has been shown in preclinical studies to have a DNA-binding agent 500 times more potent than chemotherapy drug daunorubicin in stopping tumor cell expansion.

For more information, visit the company’s website at www.CNSPharma.com.

NOTE TO INVESTORS: The latest news and updates relating to CNSP are available in the company’s newsroom at https://ibn.fm/CNSP

About BioMedWire

BioMedWire (BMW) is a bio-med news and content distribution company that provides (1) access to a network of wire services via NetworkWire to reach all target markets, industries and demographics in the most effective manner possible, (2) article and editorial syndication to 5,000+ news outlets (3), enhanced press release services to ensure maximum impact, (4) social media distribution via the Investor Brand Network (IBN) to nearly 2 million followers, (5) a full array of corporate communications solutions, and (6) a total news coverage solution with BMW Prime. As a multifaceted organization with an extensive team of contributing journalists and writers, BMW is uniquely positioned to best serve private and public companies that desire to reach a wide audience of investors, consumers, journalists and the general public. By cutting through the overload of information in today’s market, BMW brings its clients unparalleled visibility, recognition and brand awareness. BMW is where news, content and information converge.

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Months into the coronavirus pandemic, the state-legal cannabis industry is still going strong. Although the pandemic forced many industries to shut down, resulting in the loss of millions of jobs, the cannabis industry has fared quite well despite the economic crisis. Most states have seen increased cannabis sales month over month, with some even calling the industry ‘recession-proof’.

One such state is Illinois, which has seen record-breaking marijuana sales for the fifth time in a row. In September, consumers purchased more than 1.4 million marijuana products worth nearly $67 million, with almost $18 million of those sales coming from out-of-state visitors, according to the state Department of Financial and Professional Regulation. This is a slight increase compared to the 1.3 million marijuana products sold for a total of nearly $64 million in August.

In July, Illinois reported nearly $61 million in adult-use cannabis sales, beating out by a wide margin the $44,749,787 worth of cannabis sold in June.

Although the data from September doesn’t include data about purchases made through the state’s medical cannabis program, it seems to support the notion that the cannabis industry is recession-proof.

Like most states that have legalized cannabis, Illinois declared the cannabis industry essential, allowing businesses to keep operating amidst the lockdown orders.

State officials say that although the month over month increase in sales is positive economic news, they are more interested in directing cannabis tax revenue towards restorative justice measures. Most states that allow cannabis have provisions that allocate cannabis tax revenue to programs that reinvest in communities most affected by the decades’ long war on drugs and Illinois is no different.

Illinois has brought in around $52 million in cannabis tax revenue in the first six months since retail sales began in January. Back in May, the state announced that $31 million in restorative justice grants sourced from cannabis sales tax would be available. Under a Restore, Reinvest, and Renew (R3) program established by the legalization bill, the funds would be used to provide grant opportunities for “communities impacted by economic disinvestment, violence and the severe and multilayered harm caused by the war on drugs.”

Later in July, the state announced that 25% of cannabis tax revenue would go toward a social equity program. “We were not doing this to make as much money as we could, “says Toi Hutchinsons, senior cannabis advisor to Gov. J.B Pritzker. “We were actually doing this for the people.”

Many cannabis industry players like The Alkaline Water Company Inc. (NASDAQ: WTER) (CSE: WTER) believe that legalizing and regulating the industry would bring untold economic benefits, and the figures from Illinois prove this to be the case.

About CNW420

CNW420 spotlights the latest developments in the rapidly evolving cannabis industry through the release of two informative articles each business day. Our concise, informative content serves as a gateway for investors interested in the legalized cannabis sector and provides updates on how regulatory developments may impact financial markets. Articles are released each business day at 4:20 a.m. and 4:20 p.m. Eastern – our tribute to the time synonymous with cannabis culture. If marijuana and the burgeoning industry surrounding it are on your radar, CNW420 is for you! Check back daily to stay up-to-date on the latest milestones in the fast -changing world of cannabis.

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• SRAX moving BIGtoken to separate publicly-traded company through definitive share exchange with Force Protection Video Equipment Corp
• BIGtoken compensates over 16 million users for data which marketers access for fee
• Malcolm CasSelle appointed CEO of BIGtoken following tenure on SRAX’s board of directors
• BIGtoken spinoff allows SRAX to focus on rapid growth of Sequire platform

SRAX (NASDAQ: SRAX), a financial technology company that unlocks data and insights for publicly traded companies, recently announced that BIGtoken, its proprietary platform that empowers Internet users to control and profit from their data, will become a separate publicly-traded company with Malcolm CasSelle as CEO. Spinning off the platform as a separate company is expected to benefit SRAX with potential upsides while reducing costs, enabling the company to focus on Sequire, its highly successful SaaS data analytics platform geared towards the investment industry.

Subject to certain closing conditions, the definitive share exchange agreement between SRAX and Force Protection Video Equipment Corp (NASDAQ: FPVD) is expected to exchange all of the outstanding equity of BIGtoken for 88.9% of the issued and outstanding shares of FPVD. SRAX’s founder and CEO Christopher Miglino will serve as chairman of the new entity and SRAX board member Malcolm CasSelle has been appointed as CEO.

“BIGtoken has experienced wide adoption from some of the largest marketers in the world and is ready to be on its own. This move will allow SRAX to stay laser focused on the rapid growth of the Sequire platform,” said Miglino in recent statements (https://nnw.fm/kCHqV). “Our focus is to get SRAX to profitability, and this move, combined with our significant growth in Sequire, gets us much closer.”

CasSelle brings an extensive range of expertise to BIGtoken, comprised of over 20 years of leadership in several digital media startups, including SVP & GM roles at SeaChange International, a tenure as president at Tribune Publishing, CEO of Timeline Labs, and GM of Groupon’s joint venture with Tencent in China. His seven years on SRAX’s board of directors make him a powerful addition to the executive suite, stemming from experience that spans BIGtoken’s inception straight through to its present-day success.

“I’m thrilled to join BIGtoken as CEO. I’m deeply committed to BIGtoken’s mission and values and believe the company is in a great position to quickly grow its userbase and consequently expand its roster of advertisers,” noted CasSelle (https://nnw.fm/0aNhx). “Our work ahead is promising. BIGtoken is already working with large brands and agencies and we look forward to helping more brands find and engage their target audiences with our platform.”

The BIGtoken platform empowers brands to unlock the power of data by giving them the ability to target and access specific niche groups across 25,000 unique market segments. Over 16 million users provide that data through compensation agreements that reward them with cash or gift cards when they opt in to give access to their data.

For more information, visit the company’s website at www.SRAX.com.

NOTE TO INVESTORS: The latest news and updates relating to SRAX are available in the company’s newsroom at http://nnw.fm/SRAX

About NetworkNewsWire

NetworkNewsWire (NNW) is a financial news and content distribution company that provides (1) access to a network of wire services via NetworkWire to reach all target markets, industries and demographics in the most effective manner possible, (2) article and editorial syndication to 5,000+ news outlets (3), enhanced press release services to ensure maximum impact, (4) social media distribution via the Investor Brand Network (IBN) to nearly 2 million followers, (5) a full array of corporate communications solutions, and (6) a total news coverage solution with NNW Prime. As a multifaceted organization with an extensive team of contributing journalists and writers, NNW is uniquely positioned to best serve private and public companies that desire to reach a wide audience of investors, consumers, journalists and the general public. By cutting through the overload of information in today’s market, NNW brings its clients unparalleled visibility, recognition and brand awareness. NNW is where news, content and information converge.

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• Pressure BioSciences has been making a name for itself as a leader in the development and sale of proprietary intense-pressure delivery systems to the worldwide life sciences field
• PBIO is developing a novel high pressure platform called Ultra-Shear Technology (“UST”) that processes oil-based solutions into water-soluble nanoemulsions that will allow the molecules inside the oil (e.g., CBD, Vitamins) to be more readily absorbed by human biology
• Development of th proprietary new instrument – the BaroShear K45-has been proceeding well since the Company received orders for all of its planned initial build of 12 units
• Pressure BioSciences reported achieving a critical milestone in the production of the BaroDShear K45 units on Oct. 6 with the lock-in of final design specifications for the commercial model and commencement of building the initial “Alpha” model
• The Company states that once the Alpha model is built, tested and approved, an additional 14 ready-for-sale systems will be built (12 for sale) in time to fulfill plans for shipping the contracted BaroShear K45 Nanoemulsification Systems during early 2021
• The sale of the first dozen BaroShear K45 units is expected to generate up to $3 million for Pressure BioSciences’ revenue stream in just the first half of 2021
• Pressure BioSciences expects that the installation of the initial 12 commercial units will propel the sale of significantly more BaroShear K45 units during the second half of 2021 and thereafter

Life sciences technology innovator Pressure BioSciences (OTCQB: PBIO) has achieved another milestone as it nears the initial production of commercial pressure-inducing technology systems expected to revolutionize a wide variety of industries through the nanoemulsification process.

Pressure BioSciences’ proprietary, next-generation Ultra Shear Technology-based BaroShear K45 System is designed to create unique, high-quality nanoemulsions of otherwise poorly soluble oils so that they become more easily absorbed and effective in the water-based biology of human bodies.

During the weeks before news about the novel COVID-19 virus’ global spread to pandemic levels seized the reins of media coverage, Pressure BioSciences announced it was launching its UST Demonstration Laboratory as a place to showcase the technology’s potential to process cannabidiol (“CBD”) oil into true, high-quality, water-soluble nanoemulsions (https://nnw.fm/5DIAX). Several months later, PBIO announced it had reached sold-out status for its initial rollout of 12 planned BaroShear K45 systems.

On Oct. 6, the Company announced the lock-in of final design specifications for the BaroShear K45’s commercial production model, which immediately launched work on construction of the initial K45 “Alpha” unit. Once the Alpha unit is built, tested and approved, the Company will build an additional 14 units, 12 of which are earmarked as ready-for-sale systems in time for the Company to fulfill plans for shipping them during early 2021 (https://nnw.fm/pNCKb).

“Our commercialization plan for the BaroShear K45 system is initially focused on the rapidly growing hemp-derived CBD market, which is projected to reach $20 billion by 2020,” Director of Marketing and Sales Kenneth F. Micciche stated in the announcement. “We plan to install these (12 BaroShear K45 nanoemulsification) systems during the first half of 2021, which we believe will generate up to $3 million in revenue. Once these initial units are installed and in commercial use, we believe they will propel the close of multiple sales of additional BaroShear K45 systems during the latter half of 2021 and thereafter.”

The Company signed a binding letter of intent to merge with Cannaworx, Inc. (USA) and its portfolio of products and IP in April, which is expected to close shortly (https://nnw.fm/ivFt6). This merger is also expected to bring two additional companies into the new company, which will be known as Availa Bio. These companies are cosmetics industry SkinScience Labs, Inc. (owner of Dr. Denese Skin Care Products, a QVC regular) and cannabis industry Five Leaf Labs, as these additional firms are expected to be signed by Cannaworx under its brand stable once the negotiations are complete.

The UST platform not only processes oils into nanoemulsions that make the oil-based solutions more readily soluble in water, it promotes extended shelf life and/or room temperature stability for low-acid liquid foods that cannot be effectively preserved using existing non-thermal technologies. It is also expected to improve the fine silky appearance and texture of cosmetic industry products.

Patents have been issued on UST technology in China; PBIO believes that patents should begin to be issued in the United States and in many other parts of the world soon.

For more information, visit the company’s website at www.PressureBioSciences.com.

NOTE TO INVESTORS: The latest news and updates relating to PBIO are available in the company’s newsroom at http://nnw.fm/PBIO

About NetworkNewsWire

NetworkNewsWire (NNW) is a financial news and content distribution company that provides (1) access to a network of wire services via NetworkWire to reach all target markets, industries and demographics in the most effective manner possible, (2) article and editorial syndication to 5,000+ news outlets (3), enhanced press release services to ensure maximum impact, (4) social media distribution via the Investor Brand Network (IBN) to nearly 2 million followers, (5) a full array of corporate communications solutions, and (6) a total news coverage solution with NNW Prime. As a multifaceted organization with an extensive team of contributing journalists and writers, NNW is uniquely positioned to best serve private and public companies that desire to reach a wide audience of investors, consumers, journalists and the general public. By cutting through the overload of information in today’s market, NNW brings its clients unparalleled visibility, recognition and brand awareness. NNW is where news, content and information converge.

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Social media was a game-changer when it first came onto the scene. Sites like Facebook and Twitter allowed people to share and connect like they never had, and for a while, no one noticed just how harmful social media could potentially be. But a few years into the social media craze we now know that while it has its benefits, social media can have quite a negative effect on mental health, resulting in anything from depression and anxiety to cyber-bullying and feelings of inadequacy.

According to researchers at Penn State and Jinan University, social media has also caused adverse effects in some individuals during the pandemic. The researchers say that excessive use of social media for updates on the coronavirus pandemic could trigger secondary trauma and depression. “We found that social media use was rewarding up to a point, as it provided informational, emotional and peer support related to COVID-19 health topics,” says Bu Zhong, associate professor of journalism, Penn State.

“However, excessive use of social media led to mental health issues. The results imply that taking a social media break may promote well-being during the pandemic, which is crucial to mitigating mental health harm inflicted by the pandemic,” he says. Zhong describes secondary trauma as behaviors and emotions resulting from knowledge about a traumatizing event experienced by a significant other.

The researchers surveyed 320 participants living in urban districts of Wuhan, China, where the virus was first discovered. In February 2020, they gave the participants an online survey, asking how they accessed and shared health information with family members, friends, and colleagues on social media, specifically on WeChat, the most popular social media mobile app in China. The researchers used an instrument created to measure Facebook addiction to assess the participants’ use of WeChat.

The participants were surveyed using a 5-point Likert-type scale, with the survey assessing their views of WeChat in providing them with informational, emotional, and peer support as well as health behavior changes as a result of social media. More than half of those surveyed reported some level of depression, with nearly 20% of them suffering moderate to severe depression. Additionally, 80% of respondents who reported secondary trauma had a low level of trauma while 13% reported moderate trauma and 7% reported high levels of secondary trauma.

“We found that Wuhan residents obtained tremendous informational and peer support but slightly less emotional support when they accessed and shared health information about COVID on WeChat,” Zhong says. “Our results show that social media usage was related to both depression and secondary trauma during the early part of the COVID-19 outbreak in Wuhan. The findings suggest that taking a social media break from time to time may help improve people’s mental well-being during the COVID-19 pandemic.

While the technology of today is beneficial to medical development, especially when being utilized by companies like Predictive Oncology (NASDAQ: POAI), a precision medicine company that applies data and artificial intelligence (“AI”) to personalized medicine and drug discovery, the rest us of should take a step away from technology from time to time. Moderation is key to enjoying the benefits of modern technology without giving any possible drawbacks chance to manifest.

About BioMedWire

BioMedWire (BMW) is a bio-med news and content distribution company that provides (1) access to a network of wire services via NetworkWire to reach all target markets, industries and demographics in the most effective manner possible, (2) article and editorial syndication to 5,000+ news outlets (3), enhanced press release services to ensure maximum impact, (4) social media distribution via the Investor Brand Network (IBN) to nearly 2 million followers, (5) a full array of corporate communications solutions, and (6) a total news coverage solution with BMW Prime. As a multifaceted organization with an extensive team of contributing journalists and writers, BMW is uniquely positioned to best serve private and public companies that desire to reach a wide audience of investors, consumers, journalists and the general public. By cutting through the overload of information in today’s market, BMW brings its clients unparalleled visibility, recognition and brand awareness. BMW is where news, content and information converge.

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Most developed countries plan to phase out traditional carbon fuel-powered vehicles for electric vehicles (“EVs”) over the next decade or two. As EVs run on clean, renewable energy, they produce zero emissions, which is in line with the governments’ long term plans to reduce carbon emissions. However, despite being relatively cheaper to fuel (charge) and maintain than traditional vehicles, most of the EVs on the market are way too expensive for the average consumer.

So, even if they wish to switch over to clean energy, a large chunk of the population simply cannot afford it. To make them more affordable, authorities have created programs to subsidize EVs, but Koffi Pierre Yao is going an entirely different way. An assistant professor of mechanical engineering and an alumnus of the University of Delaware, Yao has received a $1 million grant to engineer a next-gen lithium-ion battery that could make electric vehicles a lot more affordable than they are now.

The $1 million grant was from the U.S. Department of Energy’s Advanced Vehicle Technologies Research Program and it will enable Yao and his team to develop a battery that will be able to power electric devices for longer and at a much-reduced cost, a move that could very well revolutionize the energy industry. “If we can make this happen, it will be a paradigm shift. We’ll be taking a game-changing step.”

Traditional lithium-ion batteries, which are used to power EVs, work by converting chemical reactions into electrical energy. Two electrodes built into the battery act as energy carriers and enable this process, a cathode and an anode. The anode is usually made of graphite, and Yao and his team are attempting to make silicon anodes. Since silicon can store and deliver as much as 10 times the energy, this could result in a battery that lasts much longer than current batteries can.

Cell phones will last much longer and electric vehicles would be able to travel even three times the distance on a single charge if these batteries see the light of day. However, Yao and his team have one hurdle to cross: as it stores and releases energy, silicon grows in volume. Compared to a graphite anode which expands by 10%, a silicon anode expands by up to 350%, and this degrades the battery. According to Yao, he can solve the problem if he can create a film that would coat the silicon anode and allow it to expand while preventing degradation. “In layman’s terms, this film will be plastic. It will be elastomeric, meaning it will stretch like rubber.”

“This is a really exciting opportunity,” says Rownak Jahan Mou, a graduate student who is part of Yao’s team. “If we are successful with the silicon coating, this could open the door for still other materials to use, and even more battery options.”

This kind of next-generation thinking is the type of innovation that aligns with companies like Net Element (NASDAQ: NETE).

About Green Car Stocks

Green Car Stocks (GCS) is a specialized communications platform with a focus on electric vehicles (EV), as well as other emerging market opportunities in the green sector. The company provides (1) access to a network of wire services via NetworkWire to reach all target markets, industries and demographics in the most effective manner possible, (2) article and editorial syndication to 5,000+ news outlets (3), enhanced press release services to ensure maximum impact, (4) social media distribution via the Investor Brand Network (IBN) to nearly 2 million followers, and (5) a full array of corporate communications solutions. As a multifaceted organization with an extensive team of contributing journalists and writers, GCS is uniquely positioned to best serve private and public companies that desire to reach a wide audience of investors, consumers, journalists and the general public. By cutting through the overload of information in today’s market, GCS brings its clients unparalleled visibility, recognition and brand awareness. GCS is where news, content and information converge.

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• Sustainable Green Team Ltd. announced series of new partnerships for its subsidiaries
• National Storm Recovery stated that it had entered into an alliance with Tree Leads Today to source contracts outside of their traditional geographical coverage area
• Mulch Manufacturing Inc., SGTM’s wholly-owned mulch producing subsidiary, announced that it had renewed its agreement to supply mulch products to home-improvement chain, Menards Inc.

Sustainable Green Team (OTC: SGTM), a leading provider of environmentally beneficial solutions for tree and storm waste disposal, has recently updated the market on the significant progress achieved by its subsidiaries, as both National Storm Recovery LLC and Mulch Manufacturing Inc. announced new partnership agreements.

National Storm Recovery LLC announced that it had formed a strategic alliance with Tree Leads Today to expand their national partnerships in a bid to obtain contracts currently outside of their geographic sphere of activity (https://nnw.fm/Mvn3p). The strategic alliance was formed when National Storm Recovery deployed its teams to assess damages from Hurricane Laura, with Tree Leads Today helping the Company partner with ArborPro of Mississippi Inc. on a recovery contract awarded for recovery work carried out in the city of Sulphur, Louisiana.

Tree Leads Today is a privately held company with a nationwide footprint. The company is focused on providing tree companies with leads on tree care projects and services. The process of generating leads is done strategically so that leads are as close to one another as possible in order to maximize productivity for TLT’s tree care partners when they are giving estimates and completing contracted jobs.

“We are honored to be partnering with such an innovative and environmentally conscious organization as Sustainable Green Team,” commented Tree Leads Today CEO Don Dowd. “Tree Leads Today believes in a pay-for-performance model. We believe in our offerings so much that we take all of the risks and only expect you to pay if we deliver.”

“This strategic alliance will amplify our national partnerships and, most importantly, increase recovery contracts far beyond our reach through our Central Florida Arbor Care subsidiary,” said SGTM CEO and director Tony Raynor. “Our new strategic alliance with Tree Leads Today removes all of our limits, opening many new opportunities for our brand, team and shareholders.”

Simultaneously, SGTM has also announced that its wholly owned subsidiary, Mulch Manufacturing Inc. (“MMI”) has been awarded a 2021 mulch packaging contract renewal from Menards Inc.

Menards operates the third-largest home improvement chain in the U.S., managing 350 stores spread across 15 states. Mulch Manufacturing Inc. has been supplying Menards with mulch products dating back to 2010, with the current contract renewal dictating that Menards would increase the number of its stores carrying MMI’s mulch products by 25% over the course of the next calendar year.

SGTM’s CEO and Director Tony Raynor commented in relation to the news, “Menards mulch packaging contract renewal brings me great pride on team and the direction we’re headed. I’m a firm believer that you’re only as strong as your team, and SGTM’s achievements and trajectory validates it.”

To learn more, view the company’s investor presentation at http://nnw.fm/UpXmd

NOTE TO INVESTORS: The latest news and updates relating to SGTM are available in the company’s newsroom at http://nnw.fm/SGTM

About NetworkNewsWire

NetworkNewsWire (NNW) is a financial news and content distribution company that provides (1) access to a network of wire services via NetworkWire to reach all target markets, industries and demographics in the most effective manner possible, (2) article and editorial syndication to 5,000+ news outlets (3), enhanced press release services to ensure maximum impact, (4) social media distribution via the Investor Brand Network (IBN) to nearly 2 million followers, (5) a full array of corporate communications solutions, and (6) a total news coverage solution with NNW Prime. As a multifaceted organization with an extensive team of contributing journalists and writers, NNW is uniquely positioned to best serve private and public companies that desire to reach a wide audience of investors, consumers, journalists and the general public. By cutting through the overload of information in today’s market, NNW brings its clients unparalleled visibility, recognition and brand awareness. NNW is where news, content and information converge.

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October 1st was International Coffee Day, and it is estimated that half of all U.S. adults consume coffee on a daily basis. You might therefore be no stranger to taking a strong cup of coffee each time you wake up feeling groggy. But, did you know that the early morning cup of strong coffee you take could be compromising your metabolism and making it harder for your blood glucose level to be regulated? New research done at the University of Bath (UK) strongly suggests that this is the case.

The research team headed by Harry Smith performed overnight experiments on 29 men and women. In one of the experiments, the study participants were asked to sleep as they normally do at night, and then consume a sugary drink just after they woke up.

In another experiment, the study participants were woken up every hour for five minutes to simulate a disturbed night’s sleep. Upon waking up in the morning, these subjects were also given a sugary drink identical to the one of the group that didn’t have their sleep disturbed.

In a third experiment, the participants also had their sleep disrupted on an hourly basis. However, this group got a strong cup of coffee upon waking up, and then received the sugary drink half an hour later.

For each of these experiments, blood samples were drawn from the study subjects after they took the sugary drink. When these samples were analyzed, it was found that taking a strong cup of coffee before you have your breakfast can compromise your body’s ability to regulate blood glucose by at least 50%. This conclusion came after the researchers noted that the participants who took coffee 30 minutes before the sugary drink had 50% more blood glucose than what was found in the experiments in which the participants didn’t take coffee before having the sugary drink.

This surprising discovery suggests that it might be better to have your breakfast first before taking your customary cup (or cups) of coffee to perk you up in the morning.

On a more positive note, the researchers found that contrary to what was previously believed, a single night of disrupted sleep, such as when insomnia strikes or you get a new baby, isn’t sufficient to compromise your metabolism.

There is need for additional research to be done on the long-term effects of sleep disruption upon our metabolism, and to what extent exercise can counter some of those effects. While it may be hard for us ordinary mortals to adjust to such research which suggests we have been doing certain things wrong all our lives, research-heavy entities like Predictive Oncology (NASDAQ: POAI) see such groundbreaking findings as a normal part of learning.

About BioMedWire

BioMedWire (BMW) is a bio-med news and content distribution company that provides (1) access to a network of wire services via NetworkWire to reach all target markets, industries and demographics in the most effective manner possible, (2) article and editorial syndication to 5,000+ news outlets (3), enhanced press release services to ensure maximum impact, (4) social media distribution via the Investor Brand Network (IBN) to nearly 2 million followers, (5) a full array of corporate communications solutions, and (6) a total news coverage solution with BMW Prime. As a multifaceted organization with an extensive team of contributing journalists and writers, BMW is uniquely positioned to best serve private and public companies that desire to reach a wide audience of investors, consumers, journalists and the general public. By cutting through the overload of information in today’s market, BMW brings its clients unparalleled visibility, recognition and brand awareness. BMW is where news, content and information converge.

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For long, doctors and researchers have been baffled by the myriad of different symptoms that people with Parkinson’s disease exhibit. According to new research that has just been published in a neurological journal called Brain, it now turns out that Parkinson’s is not just a single disease. Rather, the condition has two variants which should be managed differently.

This eye-opening research was done by a team from Aarhus University Hospital and Aarhus University in Denmark. Professor Per Borghammer and Jacob Horsager, M.D. are the researchers behind this work.

The team used advanced brain scanning techniques (PET and fMRI) to establish that Parkinson’s can originate from two different parts of the body, and that explains why the symptoms manifesting in sufferers differ.

Their research revealed that some cases of Parkinson’s start within the intestines and then spread to the other organs of the body, such as the brain. This variant was named the body-first type of Parkinson’s since the neural degeneration starts in the intestines before spreading to the neurons in the brain.

The second variant of Parkinson’s that the researchers found is the brain-first variant. The scans showed that this variant is harder to detect because no symptoms are evident until extensive damage has occurred to the neurons in the brain and the condition has spread to the rest of the body. It is therefore harder to slow down the progression of this brain-first disease.

Previous research had indicated that patients with Parkinson’s had gut microorganisms (microbiota) that differed from that of other people. However, it wasn’t clear why this difference existed. The research done by Prof. Per Borghammer and his colleague was designed to get answers explaining this difference in gut microbiota.

Their research was designed as a longitudinal study. This means that the researchers will call back their study subjects after three years have elapsed, and later at the six-year mark in order to run all the tests and scans which were done during the initial stages of the study. This study design is meant to collect comprehensive information about Parkinson’s disease (or diseases).

The research and its findings offers hope to the millions of people suffering from Parkinson’s that interventions could in future be more targeted so that the people suffering from either brain-first or body-first variants of the disease get appropriate treatment.

For example, the scientific community could look into fecal transplantation in order to slow down or even reverse body-first Parkinson’s in its initial stages when altering the intestinal microbiota can be beneficial. There is no doubt that entities like CNS Pharmaceuticals Inc. (NASDAQ: CNSP) will immediately appreciate the utility of the findings of this Danish pair of researchers.

About BioMedWire

BioMedWire (BMW) is a bio-med news and content distribution company that provides (1) access to a network of wire services via NetworkWire to reach all target markets, industries and demographics in the most effective manner possible, (2) article and editorial syndication to 5,000+ news outlets (3), enhanced press release services to ensure maximum impact, (4) social media distribution via the Investor Brand Network (IBN) to nearly 2 million followers, (5) a full array of corporate communications solutions, and (6) a total news coverage solution with BMW Prime. As a multifaceted organization with an extensive team of contributing journalists and writers, BMW is uniquely positioned to best serve private and public companies that desire to reach a wide audience of investors, consumers, journalists and the general public. By cutting through the overload of information in today’s market, BMW brings its clients unparalleled visibility, recognition and brand awareness. BMW is where news, content and information converge.

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• This is the company’s first line of premium products to be introduced into the market, and will be primarily distributed in countries with the highest demand for functional and medicinal mushroom superfood products – the U.S., Canada, and Japan
• The company is working with select retailers for an imminent strategic launch date.
• The company is set to launch a premium and user-friendly shopping experience through it’s e-commerce website
• The functional mushroom industry’s current demand is forecasted to $34 billion by 2024, with a global market expected to reach $50 billion by 2025
• The market has no clear brand leader at the moment, but Rritual is intent to capitalize on its innovative product line to take this position
• Company’s current marketing plan can help achieve this goal by simplifying operations and promoting business growth with a reduced time to market

Rritual Mushrooms is emerging as a premium, leading brand in the functional food and mushroom market following the launch of its innovative suite of premium functional mushroom and adaptogenic elixirs this fall. “The health and wellness benefits of mushrooms and plant-based therapies are backed by decades of scientific research. Rritual’s new line of elixirs embraces that research and provides consumers with an easy way to get a daily dose of the powerful effects,” said Dr. Mike Hart, President of Rritual, who also oversaw the development of the new line of products (https://nnw.fm/gdqVJ).

The premium suite of products consists of three different formulas made from the company’s proprietary blend of adaptogenic herbs and organic mushrooms: Reishi Relax, Chaga Immune, and Lion’s Mane Focus.

Developed for stress support, balancing mood, and facilitating restful sleep, the Reishi Relax blend is infused with cacao, ashwagandha root, and cinnamon to provide optimal wellness. Chaga Immune, also featuring Atragulus and the proprietary immune blend created by Rritual, works to enhance immune health and strengthen the body’s stress defenses. Lion’s Mane Focus was developed for cognitive health and enhanced memory and creativity, offering a mental boost as a result of its composition that includes Rhodiola root and Ayurvedic herbs like Bacopa.

Upon release, these premium products will be available through the Rritual website and the Rritual Amazon store. Each elixir will come in a 14 stick pack or 250-gram tub. A combo pack will also be available featuring all three elixir sticks in a 14 count pack.

Rritual’s premium products are the first premium brands to hit the functional mushroom market, a fast-growing sector where demand is growing and is forecasted to rise to $34 billion by 2024. As of right now, there is no clear leader in the industry, but Rritual may take this position with the release of its new products. Globally the market for functional mushrooms is expected to reach $50 billion by 2025. The current marketing structure of Rritual shows the plan to deliver its products to the United States, Canada, and Japan, countries with the highest demand for functional and medicinal mushroom superfood products.

Since its launch in 2019, Rritual’s sole purpose has been to help every person meet the demands within their life with style and ease through mushroom adaptogens. All products are plant-based and vegan, without the use of artificial sweeteners or fillers. Each product produced by Rritual is made with the principle of creating a product with limited, yet purposeful organic ingredients.

Rritual is currently working on two different marketing strategies – e-commerce and brick and mortar. Each of these strategies will be completed in two phases. The fall release is stage one of the e-commerce strategy currently underway. The second stage of the e-commerce strategy is to use team connections to create a direct-to-consumer experience using mediums such as Costco, CVS Pharmacy, Walmart, and Vitacost.

In stage one, the brick and mortar strategy will see the launch of the premium products in four non-competing store chains that have a shared best practice agreement. The stage two plan expands upon the first, but expansion will include 11 more retailers selling the product in a set number of their stores.

The “low hanging fruit” strategy and turnkey, global services market, will significantly lower the time it will take for Rritual’s products to find their way into a leading position within the industry. These strategies also simplify operations and support the company’s scaling efforts, helping it enhance its visibility on a market waiting for a leader.

For more information, visit the company’s website at www.WeAreRritual.com. 

NOTE TO INVESTORS: The latest news and updates relating to Rritual Mushrooms are available in the company’s newsroom at https://nnw.fm/Rritual

About NetworkNewsWire

NetworkNewsWire (NNW) is a financial news and content distribution company that provides (1) access to a network of wire services via NetworkWire to reach all target markets, industries and demographics in the most effective manner possible, (2) article and editorial syndication to 5,000+ news outlets (3), enhanced press release services to ensure maximum impact, (4) social media distribution via the Investor Brand Network (IBN) to nearly 2 million followers, (5) a full array of corporate communications solutions, and (6) a total news coverage solution with NNW Prime. As a multifaceted organization with an extensive team of contributing journalists and writers, NNW is uniquely positioned to best serve private and public companies that desire to reach a wide audience of investors, consumers, journalists and the general public. By cutting through the overload of information in today’s market, NNW brings its clients unparalleled visibility, recognition and brand awareness. NNW is where news, content and information converge.

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Statistics show that the U.S. gets 80% of its rare earth elements from China, and now that there is tension with China, there are fears that the Asian country could “weaponize” rare earth elements in its trade war with the U.S. by cutting off supplies to starve U.S. industries that need these elements. The industries in which rare earths are used include medical devices, advanced weapons systems, wind and solar energy, electric vehicle making and so many others. However, there is no need for panic regarding the Chinese dominance of the supply chains of rare earth elements, and here is why.

Local Production Can Be Ramped Up

The name “rare earth elements” often misleads people into thinking that it is hard to find these products in the earth. However, this isn’t true because rare earths are quite common. The only challenge is that they occur hidden in other ores, and complex as well as costly processes have to be performed to extract and purity these rare earths.

At the moment, China has the biggest number of purification facilities for rare earths, but a mine for these elements exists at Mountain Pass in California. If China cuts supplies, the owner of this mine would simply ramp up production and keep U.S. industries operational.

Sourcing Can Be Obtained Elsewhere

In the event that China restricted rare earths exports to the U.S., manufacturers can turn to suppliers elsewhere to address their needs. For example, Australia has one of the largest rare earth elements processing facilities outside China, and they can step up production quickly to meet the increased demand.

Existing Mining Companies Can Pivot to Rare Earths

When supply is low and demand is high enough, it is possible for existing mining companies to expand their operations and start separating rare earths from the waste currently generated by their operations.

Industries Can Tweak Their Rare Earths Needs

If push comes to shove, industries that use rare earth elements could be forced to look for ways to eliminate or reduce the quantity of rare earths that they use. This reaction isn’t unprecedented, as Japan automakers developed hybrid car motors which did away with or reduced the need for rare earth elements after China cut its exports to Japan in 2010. Oil refineries also reduced their rare earths needs during that scare, and so did glassmakers. This therefore goes to show that innovation can respond to supply shortages and come up with alternatives in the face of rare earths supply shortages instigated by China’s trade war with the U.S.

As you can see, there will be no doom and gloom if China decided to cut off supplies of rare earth elements to the U.S. Lots of options exist, and a lot of good could actually result from China restricting exports to the U.S.! This is probably the same view that is held by mining entities like Energy Fuels Inc. (NYSE American: UUUU) (TSX: EFR).

About MiningNewsWire

MiningNewsWire (MNW) is a specialized communications platform focused on developments and opportunities in the global resources sector. The company provides (1) access to a network of wire services via NetworkWire to reach all target markets, industries and demographics in the most effective manner possible, (2) article and editorial syndication to 5,000+ news outlets (3), enhanced press release services to ensure maximum impact, (4) social media distribution via the Investor Brand Network (IBN) to nearly 2 million followers, and (5) a full array of corporate communications solutions. As a multifaceted organization with an extensive team of contributing journalists and writers, MNW is uniquely positioned to best serve private and public companies that desire to reach a wide audience of investors, consumers, journalists and the general public. By cutting through the overload of information in today’s market, MNW brings its clients unparalleled visibility, recognition and brand awareness. MNW is where news, content and information converge.

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